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Cartagena’s Museum of Modern Art (Museo de Arte Moderno de Cartagena) contains a somewhat modest collection of about 300 works, most of which are paintings or sculptures donated by Colombian and other Latin American artists, including Enrique Grau and Oswaldo Vigas. The colonial-era building housing the museum is located within the walls of the historic part of the city; as such, it can easily be included in a morning’s or afternoon’s explorations, whether independent or guided.

It’s fun to imagine that Xcalak, a sleepy coastal village south of Mahahual on Mexico’s Costa Maya, is what the entire Caribbean coast of Mexico looked like before the creation of the Cancún megaresort in the 70s. No Spring breakers, no cruise ships, no thumping beachside clubs, no big hotels. Just white sand and palapas, palm trees and pelicans, hammocks and fishing boats. Just you in secluded relaxation away from it all. Several clean and basic hotels are located on the old coast road and fresh, cheap seafood is abundant at local favorite Toby’s. Dive and snorkel trips can be arranged at XTC Dive Center (www.xtcdivecenter.com), located about 300m north of town.

Cozy, romantic, and right on the beach, this Sanibel restaurant is perfect for a special-occasion dinner. Book a table for the hour leading up to sunset, then linger over New American cuisine like lobster tempura, blue crab cakes, and roasted oysters with chorizo. Also available are meat-centric dishes like short ribs, grilled filet mignon, and Hudson Valley foie gras.

Many temptations are under one roof at the Langham, New York, Fifth Avenue. This polished hotel bucks the trend of tiny Midtown hotel rooms with spaces that begin at 420 square feet and stretch up to apartment-style accommodations with full kitchens—an ideal setup for families. The style is modern and refined, from the sweeping staircase that connects the lobby to the Michelin-rated Ai Fiori restaurant of chef Michael White on the second floor. The hotel doubles as an art gallery for the work of American artist Alex Katz, whose bold figurative paintings hang on the walls throughout the hotel. There’s also Chuan Body + Soul, a day spa based on the principles of Chinese Medicine.

Dieppe Bay is ringed by black sand—a reminder that St. Kitts was formed by volcanoes. It’s also the site of the first European settlement in the eastern Caribbean, a French colony established in 1538 that was destroyed by the Spanish just two weeks after its founding. Beyond its historic significance, however, Dieppe Bay is simply a peaceful, palm-lined beach on the north end of the island. An offshore reef keeps the water calm for swimming and snorkeling, and Arthur’s restaurant is nearby for when you’re craving some fresh fish and vegetables.

At the beginning of the 20th century, a physics professor in Massachusetts inherited a ton of money. He promptly headed for the South Pacific, settling there and founding what’s now the Harrison Smith Botanical Garden. Maybe Smith had a slight Noah complex: He brought in plants from around the world, which means an African flower might sit next to a South American fern. The problem is that he inadvertently killed off the native plants with his imports. Still, the garden is a lovely spot to wander around, a sampler box of world botany.

While the waters of the massive Great Salt Lake are too salty to sustain anything more than algae, brine shrimp, and brine flies, the wetlands on its north and east shores are critical habitats for millions of migratory birds, making it a top-notch bird-watching destination. There are three state parks adjacent to the lake, including the Great Salt Lake Marina, where you can launch sailboats and kayaks. And if the water level is low enough, you’ll be able to see the famous Spiral Jetty, a 1,500-foot-long art installation made of salt-encrusted basalt slabs.

Two of Manila’s most famous churches can be found in close proximity to each other within the historic walled city of Intramuros. The 16th-century San Agustin Church, a UNESCO World Heritage Site, is the oldest church in the Philippines and was the only building in Intramuros to survive heavy bombing in World War II. It boasts an impressive interior with trompe l’oeil effects, a Baroque pulpit and a majestic pipe organ, and the museum houses treasures of Old Manila. A few blocks away, the Manila Cathedral, restored many times since the original version was built 450 years ago, hosts religious artworks and sacred relics and was visited by Pope Francis in 2015.

Thermal springs dot the countryside just north of San Miguel, some as close as a five-minute taxi ride away. Newest—and closest among them—is the Spa at Los Senderos (pictured above), with an adjacent sandy lakeshore for a day-at-the-beach facsimile. In fact, this is a wider residential and ecological project that includes vineyards and organic orchards. Older spas like La Gruta, Escondido Place, and Taboada merit daylong excursions, with lunch being served while you recline in your chaises longues. And the Mayan Baths, with an underground rock-walled grotto complete with candles and piped-in music, can make for a romantic evening, even including a buffet dinner. (That said, double-check the somewhat irregular schedule.)

It’s hard to go wrong with Italian food in Boston’s North End, but one surefire way to go right is to turn left from the door of the Paul Revere House and slip inside the historic town house that’s home to Mamma Maria, an unmissable fine-dining restaurant facing North Square. Settle into the serenely elegant dining room overlooking the square to feast on classics like terrine of suckling pig, veal osso buco, Tuscan-style rabbit pappardelle, and a wide selection of seafood dishes from local waters. The uninitiated may mutter a “mamma mia” at the prices, but for Northern Italian in the North End, Mamma Maria rules the house.

Set on 4,200 secluded acres of hillocks, ponds, and gardens at the foot of the Tennessee Smoky Mountains, this award-winning resort, a member of the prestigious Relais & Châteaux brand, is awash in genteel luxury, from its splendid spa to its exquisitely appointed rooms, suites, and cottages. But make no mistake, the family-owned property takes the “farm” in its name to heart: Its James Beard Award–winning restaurant, The Barn, as well as the more informal Dogwood restaurant, were early leaders in the farm-to-table movement, welcoming guests who come to pay homage to the inn’s self-described foothills cuisine.

In addition to several gardeners, the farm employs its own butcher, cheese maker, and beekeeper, along with a preservationist who makes pickles, jams, and jellies. The staff raise their own sheep, pigs, and chickens, and forage the land for mushrooms, berries, ramps, wild crab apples, and muscadines—which you’ll share at the table with other guests (all meals are included in your stay). Thankfully, a roster of on-site activities—including cycling, wakeboarding, archery, paddleboarding, hiking, fly-fishing, swimming, tennis, and golf—allow you to indulge without feeling guilty.

This national park is an ecological preserve with upland watersheds, mangrove forests, and estuarine and marine environments that support threatened and endangered species. The park also includes the Columbus Landing Site, a National Historic Landmark that is the only known place where members of a 1493 expedition led by Christopher Columbus (his second voyage) set foot on what is now United States territory. Columbus and his men met a tribe of Caribs here, so it was the first documented encounter between American Indians and Europeans.

Situated on the second floor of the Langham Hotel, this restaurant is open around the clock—and after tasting the team’s handiwork, we’re all the more thankful. Seasonal American cuisine is the specialty here, a focus that chef Ricardo Jarquin honors in plates like the Charred-Tar (a steak tartare twist with tenderloin, A1-sauce aioli, fried quail eggs, and truffle oil), watermelon salad (a summer favorite that includes shrimp, jicama, and cucumbers), and grilled Nigerian prawns (with lemon butter and herbs). Whatever you do, save room for dessert; pastry chef Scott Green has a knack for sweets that look as good as they taste. Case in point: the lemon pavlova, with lemon cream, coconut dacquoise, and lemon croutons.

Australia’s most famous beach has played many roles throughout history. In 1907, a group of local swimmers became the world’s first lifeguards; during World War II, it was fortified by barbed wire and iron stakes; and over the last few decades, it has become a play land for international backpackers. More recently, the bohemian surf hood has morphed into a lively dining and shopping hub, with restaurants ranging from standbys like Sean’s Panaroma to the friendly burger joint Bonditony’s to Italian favorite Da Orazio Pizza and Porchetta, opened by Icebergs Dining Room owner Maurice Terzino. (Don’t miss the pool and sauna at Icebergs either.) Once fed, check in at the QT Hotel, shop along Gould Street, and walk the stunning Bondi to Coogee coastal path.

Anyone can swim in this glorious pool for a mere $5.50. Mon-Fri: 6:00-6:30pm Sat, Sun: 6:30-6:30pm Closed Thursdays.

If shopping is on your agenda, be sure to stop at Mongoose Junction, at the north end of Cruz Bay where North Shore Road heads out of town. The open-air mall is small but attractive, made of local stone and mahogany and landscaped with tropical plants. Mongoose Junction is packed with art galleries, restaurants and boutiques selling locally made clothing and jewelry. Before you leave, check out St. John Scoops, which makes almost 100 flavors of ice cream and sorbet (like mango, passion fruit and salted caramel) and serves them up in hand-rolled waffle cones. Delicious superfood smoothies are on the menu, too.