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La Specola, one of the oldest science museums in Europe, contains a collection of specimens of the natural world—some of which date back to the 16th century. It includes strange and wonderful objects ranging from tiny iridescent green beetles and multicolored butterflies to whale and rhinoceros skeletons. There’s even a hippo, preserved by taxidermy, that was once pet to the Medici family and lived in the Boboli Gardens! The extraordinary, if slightly creepy, anatomical waxes filling the last four rooms of the museum were once used to train Florentine medical students. The frescoes and elaborate pietra dura inlays that decorate the walls and ceilings detail Italian scientific achievements.

One thing you’ll likely notice when walking the streets of Cuzco is how many places advertise pizza. If you’re dying for a slice, there’s no better spot than La Cantina. Primarily a wine bar—bottles of all-Italian vintages line the walls—this place also happens to serve the best pizza in town, with a delicately thin crust topped with ingredients like authentic salami, prosciutto, arugula, olives, a variety of cheeses, and more. You’ll also find imported meat and cheese plates, lasagna, bruschetta, and salads. If you’re lucky, there’s tiramisu at the meal’s end, plus artisanal limoncello. Go for the wine, but be sure to try the food while you’re there.

For a welcome reprieve from city life, steer to the northwest part of Santa Fe to find this network of 25 miles of easy, multipurpose trails. Simply stroll, take a long run, or hop on horseback to wind through a high-desert landscape dotted with wildflowers and sagebrush, under a vast blue sky. For the adventure seekers, there’s plenty of mountain bike terrain (for all levels), and for advanced BMX riders, a designated Trash Pit welcomes more technical freestyle riding and stunts.

The longest-operating resort in the area, La Quinta is such a landmark that the town was named after it (rather than the other way around). The hotel has aged gracefully: In 2016, it celebrated its 90th anniversary. Recent renovations melded Waldorf Astoria amenities with original Saltillo tile floors, vintage relics, and photography from its Old Hollywood heyday. The Spanish-style whitewashed property is sprawling, with 620 guest rooms, 98 villas, and 41 temperature-controlled pools across its 45 acres. That size allows guests to choose their own adventure: Book a Deluxe Casita close to the smaller, kid-friendly pools. Traveling without children? Stay in a Starlight Casita, which has both an indoor and outdoor fireplace, and retreat to the adults-only plunge pool for chilled drinks and music. Unlimited fitness classes—including yoga, meditation, and suspension training—plus five award-winning golf courses and 23 tennis courts help balance the indulgence that can easily occur at the seven eateries. Pro tip: To combat the effects of any sun damage, try the Citrus Escape at the holistic spa. Finish the day at Morgan’s in the Desert, open exclusively for dinner, and pair the sunset view with an herbaceous gin and elderflower liqueur cocktail known as the Basil Me Down.

In a city known for its breakfast tacos, it can be hard to decide where to start your day. One place that will never disappoint, however, is La Villita Cafe. The options here are simple—think bean and cheese, potato and egg, and chorizo and egg—but everything is delicious, especially the brisket and egg taco. When you’re done eating, check out the neighboring La Villita art community, which provides a window into San Antonio’s diverse past.

When he was training in Michelin-starred restaurants, chef Dominique Le Stanc dreamed of opening a small place where the art of cooking was more important than efficiently running a restaurant. La Merenda is that place—no phone, no credit cards, the only business being the food. The chef’s skills shine with dishes like fried zucchini blossoms, a zingy pistou-laden pasta, and, for dessert, melty sautéed figs. Guests, many of whom are locals, are seated elbow to elbow in the tiny dining room with a clear view of the gifted chef at work in the open kitchen.

For comida típica (home-style food) in Guadalajara, you can’t beat La Chata, an old-school, diner-style restaurant that’s been around since 1942. Generations-old recipes for enchiladas, flautas, and the platillo jalisciense (fried chicken and five sides) along with hefty portions and low prices keep locals lined up around the block. However, the line moves fast and the food comes out faster, so you won’t be waiting for long.

The precariously leaning, step-gabled houses that were joined to form this elegant dining room date back to 1614, and many of their original interiors remain intact, with beautiful delft-tiled walls, wood beams, and wide-plank floors. The restaurant’s name, which translates to “the Silver Mirror,” serves locally sourced ingredients, such as Zeeland mussels, North Sea shrimp, and Dutch beef, with a contemporary flair; the award-winning wine list includes some 225 bottles from around the world. Order à la carte or try one of the tasting menus, which run from four to seven courses and are priced from €49.95 to €79.95 (about $60 to $95) without wine.

San Juan’s oldest restaurant has been serving up Puerto Rican and Spanish flavors since 1848. La Mallorquina, set right in the heart of Old San Juan, is known for rustic, home-style dishes like salt cod fritters, arroz con pollo (chicken with rice) and pasteles (similar to tamales).

Check your email and share your pictures of your fabulous Amalfi Coast vacation on Facebook and Instagram, all while you enjoy a cold drink with a view of the Spiaggia Grande. La Brezza Net Art Café has strong Wi-Fi and is open all day for breakfast, lunch, snacks, aperitivi, and dinner. The menu includes big salads and simple sandwiches. The lemon granita is particularly good. Below the outside terrace, the BioBrezza counter serves fresh fruit smoothies and juices.

You don’t have to be old enough to drive to have fun at LVMGP; four tracks, three amusement rides, one super-slide, and tons of arcade games make the destination a fun spot for the entire family. Go-carts headline the action, with three speed tracks (and a course for kids that often devolves into a bumper-cars situation). On one of the speed tracks—dubbed the Adult Gran Prix—cars get up to 60 miles per hour and feature technology that keeps tabs of how fast you’re going; during your “race,” your time is displayed on a leader board so you can compare and compete with your friends. Elsewhere at the facility, there’s a small roller coaster and a giant 90-foot slide. Inside, the arcade takes center stage, with air hockey, video games, and four games of pop-a-shot, as well as a restaurant.

One of the most romantic hideouts on Bonaire, La Balandra is designed to make you feel like you’re dining on an old Spanish ship when, in fact, you’re ensconced in the Harbour Village Beach Club. Cruise passengers have two options here: Pay an approximately $50 resort fee that includes a credit toward the restaurant, but also gives you access to the private beach, lounge chairs, dive shop and other facilities—or go for the restaurant only. Either way, call ahead to reserve (599-717-7500).

Della’s, the breakfast-and-lunch-only restaurant at the Delano Las Vegas, prides itself on sourcing ingredients from local farmers and growers—yes, they really exist in the middle of the Nevada desert. The menu has options that can satisfy diners with all sorts of dietary restrictions: vegan, gluten-free, vegetarian, and more. For breakfast, you can taste the difference that comes with farm-fresh produce, especially in the egg dishes. At lunchtime, the off-menu ramen bowl features a savory mushroom broth with a pork shank, house-fermented cabbage, and a slow-poached egg. Della’s is also one of the only places on the Strip where you can get cold-pressed juice made to order. The overarching commitment to sustainability extends beyond the menu: Glasses here are created from recycled liquor bottles from Vegas clubs.

After a day spent exploring Montjuïc’s gardens and museums, this cozy corner restaurant in nearby El Poble-Sec makes for an ideal dinner stop. Simply decorated, with bright green walls, a long wood bar, and a handful of tables, La Platilleria doesn’t have a fixed menu; rather, the kitchen offers a daily selection of seasonal, locally sourced small plates. There are Spanish stalwarts like patatas bravas, pan con tomate, and Ibérico ham, but it’s worth trying the specials, which might include a rich dish of braised oxtail atop polenta, or osso buco with sweet potatoes. A small but well-curated selection of Spanish wine, cava, and craft beer is available—if you’re feeling daring (or thrifty), order a 3 euro ($3.35) pinguino, a penguin-shaped carafe of rustic local wine.

One of Cancún’s oldest restaurants, La Habichuela was a 1970s original whose owner wanted a place to hang out with friends. It’s become an upscale dining room featuring local Mayan recipes alongside Mexican-Caribbean fare. The now iconic restaurant borders downtown’s Las Palapas Park, and has a charming backyard garden adorned with twinkly lights and climbing vines. Start the evening with balché, an ancestral Mayan drink made from the bark and roots of the balché tree that have been soaked in honey and water. For your entrée, try the amaranth fish bathed in flavorful tamarind and mango vinaigrettes.