Built in 1443, this iconic Gothic building is immediately recognizable from its stately turrets and steep, colorfully tiled roof. A working hospital until the 1970s, it now functions as a medical museum and renowned wine estate, with 148 acres of vineyards that produce prestigious wines sold at auction every November. A walk through its beautifully preserved interiors will transport you to medieval times, when the poor relied on the charity of wealthy supporters who funded the hospital. Don’t miss the 18th-century pharmacy, complete with medieval surgical instruments, and the soaring Grand Salle.