You can enter the old colonial city—called the Casco Viejo—between the Mercado del Marisco and Sabores del Chorrillo. Panama City was moved here back in 1673, after being sacked and burned in 1671. The district today is resplendent with vintage hotels alongside modern edifices and landmarked historic buildings. The downtown sightseeing agenda is easy: Cross the Plaza de Francia and Las Bóvedas; visit the fascinating Canal Museum (that’s mandatory!); and then finish the day with a beer on one of the many terraces that line plazas Bolívar, Herrera, or Independencia. With luck, you’ll have enough time to visit several restored churches.