Calz. de Amador 136, Panamá, Panama

It cost a whopping $60 million to build this 4,000-square-meter (43,056-square-foot) space covered by shiny orange, blue and red canopies that mimic the tops of traditional tin-roofed houses. An affiliate of the Smithsonian, Frank Gehry’s Biomuseo showcases the region’s biodiversity, which dwarfs that of the rest of North America. The museum anchors the Amador Causeway, which was made from canal landfill and is today a palm-tree-lined playground of marinas, restaurants, nightclubs and boutiques.

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