Don't be fooled by Apothéke's gritty exterior. This is not your typical cocktail bar. Once you pass through the entrance doors, things start getting interesting.
For one thing, the bartenders are wearing apothecary outfits and the menu consists of "prescriptions." The decor is inspired by the rise of the apothecary in Europe and the absinthe dens that existed in 19th century Paris.
It's not just your cocktail that you are choosing - you are also selecting your mood. The Menu is broken up into several categories: Health & Beauty, Aphrodisiacs, Stress Relievers, Pain Killers and Stimulants to name a few.
If you are heading there late at night during the week or on the weekend except a bit of a line. Those who learn about this place tend to become regulars. The closest subway is the B,D at Grand Street or the J at Canal or Chambers Streets.
Every time I visit New York, I try to visit Apotheke. It's dark and stylish room with a little jazz band in the corner setting a smooth, prohibition era vibe, fits perfectly with the well thought out drinks.