Located in Railtown, an industrial and up-and-coming part of Vancouver, Vancouver Urban Winery has one of the most relaxed and lively tasting rooms in the city. They produce some of their own wine, but also have range of excellent wines from British Columbia (all on tap!). On my first visit I was surprised to see some favorites of mine from around the province were available on tap - you can still order a carafe or two. Not just for wine lovers - this is also the home of Postmark Brewing, so buy a flight or bring your growler.
The tasting room gets busy after work, and don't forget to order food; you could easily turn after-work drinks in this space into a fun dinner.