I would say apart from the Top of the Rock at Rockefeller Centre, this is my favourite view of Manhattan.
It is a jawdropping view. Even though it was a rainy day, this was the perfect backdrop to have a Dark and Stormy and take in the (hipster) scene.
I highly recommend visiting in the afternoon if you are visiting on a weekend. I have heard it can get crowded and quickly.
Another note: it is VERY difficult to get a cab from the Wythe, especially if you are going into the city.