While it may not get the attention that Brussles and Bruges receive, Antwerp is the city in Belgium that has the most to offer. Here you have a blend of architecture, the old, the new, high fashion, and good food.
Arrive in style at the Centraal Station and take time to admire the work of art that the train station is in its own right. Next head to the Rubenshuis (museum.antwerp.be). The museum is actually Rubens home and is as worthy of viewing as the art. The audio guide is very infomative!!!
After the museum walk to the Meir (the main shopping avenue) and take an immediate left into "The Chocolate Line" for some of the freshest and best chocolate to be found in Belgium. Follow the Meir until you reach the cathedral (www.dekathedraal.be) where you can take the lessons learned from your visit to the Rubenshuis and apply them to the works of art found in the cathedral. If you are hungry by now there is an excellent Italian restaurant called "Verona" at the base of the cathedral. Prefer some traditional Belgin cuisine?? Then head right past the cathdral to the Grote Markt and you'll find one of the prettiest squares in Belgium!
And don't overlook Antwerp when it comes to the Christmas Market route. The city is lit up and there are surprises to be found on many of the squares!